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Large amounts of SRF can be seen by ophthalmoscopy (looking into the eye) and ultrasound imaging. Cancers need new vessels in order to grow.

“S,” Subretinal fluid (SRF) is created by poorly formed or new, “neovascular” blood vessels within the tumor.Lipofuscin is best seen with a photographic test called Fundus Auto Fluorescence imaging, or FAF. This finding tells us that that either the underlying tumor is destroying the overlying tissue or itself is degenerating. “O,” Orange Pigment Lipofuscin (OPL) a metabolic side product of cell death.Finger has developed the mnemonic device “MOST” to help eye care specialists to determine if the intraocular tumor is a melanoma. This includes asking questions about your medical history, examining both of your eyes, looking into the eye through a dilated pupil, performing an ultrasound examination, and specialized photography (to examine the circulation within the choroidal melanoma). Choroidal melanomas can spread to other parts of the body.Įye cancer specialists can determine if you have a choroidal melanoma by performing a complete eye examination with testing. That said, choroidal melanomas are rare with 5 to10 out of each million people diagnosed with a choroidal melanoma each year. Therefore, when melanoma happens in the choroid, they are called “choroidal melanoma,” the most common primary intraocular malignancy in adults. It is those melanocytes that can turn into malignant melanoma.

Further, the pigment producing cells, “melanocytes” are primarily found in the vascular uveal layer. From outside to inside there is: the white sclera, a blood vessel layer called the uvea (choroid, ciliary body and iris) and an inner retinal layer. Finger, MD Description Choroidal Melanoma

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